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【流式學習】一起聊聊PNH和FLAER的故事
國際PNH興趣小組將PNH分為以下三類
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經典型PNH:該患者有典型的溶血和血栓形成；
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合并其他骨髓衰竭性疾病:如再生性貧血（AA）或骨髓增生異常綜合征 (MDS)；
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亞臨床型PNH：患者有輕微的PNH克隆，但沒有溶血和血栓臨床證據。
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品名 |
貨號 |
規格 |
品牌 |
|
FLAER(Alexa488 proaerolysin variant) solid format |
FL1-R |
25 ug |
Cedarlane |
|
FLAER(Alexa488 proaerolysin variant)liquid format |
FL1S-R |
25 ug |
Cedarlane |
|
FLAER(Alexa488 proaerolysin variant) solid format |
FL2-R |
50 ug |
Cedarlane |
|
FLAER(Alexa488 proaerolysin variant)liquid format |
FL2S-R |
50 ug |
Cedarlane |
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Keeney M, Illingworth A,Sutherland DR ,etc. Paroxysmal Nocturnal Hemoglobinuria Assessment by FlowCytometric Analysis Clin Lab Med. 2017 Dec;37(4):855-867.
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Sutherland DR, Kuek N, Azcona-Olivera J,etc. Use of a FLAER-based WBC assay in the primary screening of PNH clones. Am J Clin Pathol. 2009 Oct;132(4):564-72.
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Illingworth AJ, Marinov I, Sutherland DR.Senstive andaccurate identification of PNH clones based on ICCS/ESCCA PNH ConsensusGuidelines-A summary. nt J Lab Hematol. 2019May;41
